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Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2

✍ Scribed by Fiona E. Harrison; James M. May

Book ID
113630793
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
667 KB
Volume
46
Category
Article
ISSN
0891-5849

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Sodium-dependent vitamin C transporter 2
Sodium-dependent vitamin C transporter 2 (SVCT2) is necessary for the uptake of L-ascorbic acid into Schwann cells
✍ Burkhard Gess; Christina Lohmann; Hartmut Halfter; Peter Young πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 458 KB

## Abstract Ascorbic acid has been shown to be an essential component for __in vitro__ myelination and to improve the clinical and pathological phenotype of a mouse model of Charcot–Marie‐tooth disease 1A. The mechanism of ascorbic acid uptake into peripheral nerves, however, has not been addressed