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Vitamin A levels in patients with CF are influenced by the inflammatory response

✍ Scribed by Ristan M. Greer; Helen M. Buntain; Peter J. Lewindon; Claire E. Wainwright; Julia M. Potter; Joseph C. Wong; Paul W. Francis; Jennifer A. Batch; Scott C. Bell

Book ID
119288326
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
140 KB
Volume
3
Category
Article
ISSN
1569-1993

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## Highlights •The inflammatory response increases the expression of RAC3 __in vitro__ and __in vivo__. •TNF induces the increase of RAC3 at transcriptional level through NF-κB activation. •Glucocorticoids also induce the increase of RAC3 expression levels. •RAC3 appears to be essential for NF-κ