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Visualization of human prenatal development by magnetic resonance imaging (MRI)

✍ Scribed by Kohei Shiota; Shigehito Yamada; Tomoko Nakatsu-Komatsu; Chigako Uwabe; Katsumi Kose; Yoshimasa Matsuda; Tomoyuki Haishi; Shinobu Mizuta; Tetsuya Matsuda

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
222 KB
Volume
143A
Category
Article
ISSN
1552-4825

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✦ Synopsis

Abstract

It is essential to visualize the structures of embryos and their internal organs three‐dimensionally to analyze morphogenesis; this used to rely solely on serial histological sectioning and solid reconstruction, which were tedious and time‐consuming. We have applied imaging with a magnetic resonance (MR) microscope equipped with a 2.35 T superconducting magnet to visualize human embryos; we were successful in acquiring high‐resolution sectional images and in identifying the detailed structures of major organs. The imaging process was facilitated by using a super‐parallel MR microscope. A dataset of MR images of more than 1,000 human embryos, now collected, will be important for future biomedical research and for education. © 2007 Wiley‐Liss, Inc.

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