Visualising fouling of a chromatographic
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Sun Chau Siu; Rihab Boushaba; Vithaya Topoyassakul; Alex Graham; Sorwar Choudhur
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Article
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2006
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John Wiley and Sons
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English
⚖ 225 KB
Confocal scanning laser microscopy (CSLM) was used to visualise the spatial location of foulants during the fouling of Q Sepharose FF matrix in finite batch experiments and for examining the subsequent effectiveness of clean-in-place (CIP) treatments in cleaning the heavily fouled beads. Beads were