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Visual evoked potential in the diagnosis of dementia in people with down syndrome

✍ Scribed by Dr. V. P. Prasher; V. H. R. Krishnan; A. Blake; D. J. Clarke; J. A. Corbett

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
447 KB
Volume
9
Category
Article
ISSN
0885-6230

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The diagnosis of dementia in people with Down syndrome (DS) remains controversial. In this study DS patients who had a diagnosis of clinical dementia according to modified DSM‐III‐R criteria were assessed using the flash (P2) and pattern‐reversal (P100) visual evoked potential (VEP). Abnormal VEP recordings were apparent in both demented and non‐demented subjects. None of the demented subjects had the characteristic (P2–P100 latency difference) VEP changes reported in adults in the general population suffering from dementia. The VEP is unlikely to be a useful tool in the diagnosis of dementia in people with DS.

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