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Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine

✍ Scribed by Sommer, Grit; Garten, Antje; Petzold, Stefanie; Beck-Sickinger, Annette G.; Blüher, Matthias; Stumvoll, Michael; Fasshauer, Mathias

Book ID
120272942
Publisher
Portland Press
Year
2008
Tongue
English
Weight
290 KB
Volume
115
Category
Article
ISSN
0143-5221

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CooA is a transcriptional activator containing a b-type heme as a prosthetic group. The heme in CooA is in the six-coordinate form in the ferric and ferrous state. Although the ferrous heme is coordinated by two axial ligands, it can react easily with CO to form the CO-bound heme under physiological