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Virulence factor p60 of Listeria monocytogenes modulates innate immunity by inducing tumor necrosis factor α

✍ Scribed by Hiroshi Sashinami; Dong-Liang Hu; Sheng-Jun Li; Toshihito Mitsui; Ken-Ichi Hakamada; Yoh Ishiguro; Shinsaku Fukuda; Akio Nakane


Book ID
109309636
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
228 KB
Volume
59
Category
Article
ISSN
0928-8244

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## Abstract This study describes the involvement of the p38 mitogen‐activated protein kinase (MAPK) during interferon‐γ (IFN‐γ) signaling in fetal brain astrocytes. In some pathological conditions of brain, p38 MAPK transduces stress‐related signals, increases expression of proinflammatory cytokine