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Virtual Screening and Docking of Potential Protein Kinase B Inhibitors

✍ Scribed by Kutlu Ulgen, Sefika; Aladag, Seval; Ozkirimli, Elif

Book ID: 119209618
Publisher: Biophysical Society
Year: 2012
Tongue: English
Weight: 50 KB
Volume: 102
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.361

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## Abstract Protein kinase C (PKC) isozymes are important signal transducers in a number of cellular responses that makes PKC inhibition a topical target for drug discovery. In this study, a set of natural compounds and their derivatives (43 in total) were screened to establish their potential inhi