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Investigation of Potential Glycogen Synthase Kinase 3 Inhibitors Using Pharmacophore Mapping and Virtual Screening

✍ Scribed by Nigus Dessalew; Prasad V. Bharatam


Book ID
111368344
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
804 KB
Volume
68
Category
Article
ISSN
1747-0277

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Bruton’s tyrosine kinase has emerged as a potential target for the treatment for B‐cell malignancies and autoimmune diseases. Discovery of Bruton’s tyrosine kinase inhibitors has thus attracted much attention recently. In this investigation, we introduced a hybrid protocol of virtual screening metho