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Vinylogous carbinolamine tumor inhibitors. 6. Synthesis and antileukemic activity of 1-methyl-2,5-diphenyl-3,4-bis(hydroxymethyl)-, 1,2,3-triphenyl-4,5-bis(hydroxymethyl)-, and 1-methyl-2,3-diphenyl-4,5-bis(hydroxymethyl)pyrrole bis(N-methylcarbamate)

✍ Scribed by Anderson, Wayne K.; Halat, Michael J.; Rick, Arvela C.


Book ID
126129833
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
413 KB
Volume
23
Category
Article
ISSN
0022-2623

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✍ Suresh, J. ;Alex Raja, V. P. ;Perumal, S. ;Natarajan, S. 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 351 KB

In the title molecule, C 31 H 28 N 2 O 2 , the piperidinone ring adopts the usual twist-boat conformation. The aryl rings at positions 2 and 3 are axial and those at positions 5 and 6 are equatorial. In the crystal structure, there are no hydrogen bonds nor are there any significant Á Á Á stacking i