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Vinyl ketene rearrangement mechanism of homobullvalenone

✍ Scribed by Goldstein, M. J.; Dai, S. H.


Book ID
126880220
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
373 KB
Volume
95
Category
Article
ISSN
0002-7863

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Ketene N,O-acetals were prepared stereoselectively and submitted to a Lewis acid-mediated 1,3-rearrangement to afford C-alkylated products. The reactions proceeded in a stereoselective manner to construct a chiral quaternary carbon in high selectivity. The stereochemistry of the quaternary center wa