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Vinca alkaloids XXXIV. Preparation of des-Na-methyl-vindoline by microbiological conversion of vindoline, a major alkaloid from Vinca roseaL

✍ Scribed by Norbert Neuss; D. S. Fukuda; D. R. Brannon; L. L. Huckstep

Publisher
John Wiley and Sons
Year
1974
Tongue
German
Weight
120 KB
Volume
57
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The conversion of vindoline (II) using S. albogriseolus led to the isolation of several compounds including des‐N~a~‐methyl vindoline (III) in 8–10% yield.

πŸ“œ SIMILAR VOLUMES

Vinca Alkaloids XXXII. Microbiological c
Vinca Alkaloids XXXII. Microbiological conversions of vindoline, a major alkaloid from vinca rosea L
✍ N. Neuss; D. S. Fukuda; G. E. Mallett; D. R. Brannon; L. L. Huckstep πŸ“‚ Article πŸ“… 1973 πŸ› John Wiley and Sons 🌐 German βš– 462 KB

## Abstract Vindoline, a major alkaloid from __Vinca rosea__ ~L~ was subjected to microbiological conversion using __Streptomyces__ cultures. Several new metabolites were isolated and their structures elucidated.