Effect of base concentration on the rate
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Mieczyslaw Maฬขkosza; Tadeusz Lemek; Andrzej Kwast
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Article
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1999
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Elsevier Science
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French
โ 211 KB
Varying concentration of the chloromethyl tolyl sulfone carbanion influences the rate of its VNS reaction with 2-fluoro-4-bromonitrobenzene and changes the mechanistic scheme from thermodynamic to kinetic control. Both primary and secondary kinetic isotope effects are observed and are clearly connec