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Vibrational Circular Dichroism and Absolute Configuration of Chiral Sulfoxides: tert-Butyl Methyl Sulfoxide

✍ Scribed by Ahmed Aamouche; Frank J. Devlin; Philip J. Stephens; Józef Drabowicz; Bogdan Bujnicki; Marian Mikołajczyk


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
156 KB
Volume
6
Category
Article
ISSN
0947-6539

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The absolute configuration of the (À)-enantiomer of mirtazapine was determined by means of vibrational circular dichroism (VCD). The observed VCD of (À)-mirtazapine showed excellent correlation with the calculated VCD of the (R)-enantiomer. This is in agreement with the absolute configuration as det