Vibrational Circular Dichroism, Absolute Configuration, and Predominant Conformations of Volatile Anesthetics: Desflurane
β Scribed by Polavarapu, Prasad L.; Zhao, Chunxia; Cholli, Ashok L.; Vernice, Gerald G.
- Book ID
- 127274835
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 91 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0022-3654
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π SIMILAR VOLUMES
## Abstract Vibrational circular dichroism (VCD) measurements and density functional theory (DFT) calculations were used to obtain the first definitive assignment of the absolute configuration for the polyphenolic binaphpthyl dialdehyde gossypol and a determination of the solution conformation in C
The absolute configuration of the (Γ)-enantiomer of mirtazapine was determined by means of vibrational circular dichroism (VCD). The observed VCD of (Γ)-mirtazapine showed excellent correlation with the calculated VCD of the (R)-enantiomer. This is in agreement with the absolute configuration as det