Very short asymmetric synthesis of (1S, 3S, 5R)-1,3-dimethyl-2,9-dioxabicyclo[3.3.1]nonane via tandem enantioselective reactions promoted by one chiral borane

Synthetic utility of chiral tetrahydrofu

Synthetic utility of chiral tetrahydrofurans: Preparation of (1R, 3R, 5S)-1, 3-dimethyl-2, 9-dioxabicyclo[3.3.1]nonane

✍ Yvan Guindon; Yves St. Denis; Sylvain Daigneault; Howard E. Morton 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 246 KB

The use of the lodoetherlflcatlon reaction for the selective preparatlon of optically active w-2,4-dlsubstltuted tetrahydrofurans and the use of the latter compounds as precursors of s-1,3-dlols 1s exempllfled In the synthesis of (lR,3R,5S)-~-1,3-Dlmethyl-2,9-Dloxabicyclo [3.3.l]nonane(]).