Versatile prostaglandin synthesis. Use of a carboxy-inversion reaction
β Scribed by Kienzle, Frank; Holland, George W.; Jernow, Jane L.; Kwoh, Shuan; Rosen, Perry
- Book ID
- 121392632
- Publisher
- American Chemical Society
- Year
- 1973
- Tongue
- English
- Weight
- 434 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
By using respectively one equivalent of the pmpafgyl zinc Mcolmlate and silylated pmpargyl bromide, the preparation of 2-me/hylenc-5-trimethylsilyl-pent-4-yn-l-ol was improved. This latter is the lm~'ta'sur of the com~pcmding aldehyde whkh was used for the first time as a dienophile in [4+2] reactio
Iodonium ylides of methyl 3-oxo-trans,trans-6,8-tetradecadienoate (1) and diprotected methyl 3,5-di(tbutyldimethyl-silyloxy)-2,6,8-tetradecalrieneoate (5) undergo regio-and stereoselective inwamolecular cyclopropanation with Cu(I)CI catalysis to form key bicyclo[3.1.0] intermediates for prostaglandi
A Versatile Synthesis of Tricyclic Analogues of Quinolone Antibacterial Agents: Use of a Novel Reformatsky Reaction. -Nine pyrrolo(1,2-a)quinolone-4-carboxylic acids (IV) are synthesized involving Reformatsky reaction of (I) with diethyl bromomalonate and subsequent cyclization as the key steps. Co