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Versatile and Efficient Solid-Supported Synthesis of C3-Anchored Monocyclic β-Lactam Derivatives

✍ Scribed by Méndez, Luciana; Testero, Sebastián A.; Mata, Ernesto G.

Book ID
111963540
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
158 KB
Volume
9
Category
Article
ISSN
1520-4766

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A practical method for solid phase organic synthesis has been developed using the known, but heretofore underutilized, 4-hydroxythiophenol linker of Marshall and Liener. The utility of this linker is demonstrated by the synthesis of 1,2,3,4-tetrahydro-8-carboline-3carboxamides and -2,3-bis-lactams.