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Verapamil and drug metabolism by the cytochrome P450 isoform CYP1A2

✍ Scribed by U. Fuhr; B. G. Woodcock; M. Siewert


Publisher
Springer
Year
1992
Tongue
English
Weight
167 KB
Volume
42
Category
Article
ISSN
0031-6970

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Polycyclic aromatic hydrocarbons (PAHs) are a ubiquitous class of environmental contaminants. The compound phenanthrene is a model PAH. A novel fluorometric method for measuring phenanthrene metabolism in vitro was developed and verified with direct measurement of [ 14 C]phenanthrene using dog liver