A case of veno-occlusive disease of the liver with fatal outcome after dacarbazine (DTIC) therapy for melanoma is reported. There was a fulminant clinical course from start of symptoms until death. At autopsy the liver was enlarged and firm with signs of venous congestion. Smalland medium-sized hepa
Veno-occlusive disease and peliosis of the liver after thorotrast administration
β Scribed by Dejgaard, Anders ;Krogsgaard, Kim ;Jacobsen, Marianne
- Publisher
- Springer-Verlag
- Year
- 1984
- Tongue
- English
- Weight
- 667 KB
- Volume
- 403
- Category
- Article
- ISSN
- 0174-7398
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## Introduction. Hepatotoxicity consistent with the clinical diagnosis of veno-occlusive disease (VOD) of the liver has been suspected after conventional anti-cancer chemotherapy in children. Methods. To establish the incidence of hepatotoxicity and its relationship with VOD, we analyzed toxicity