The murine local lymph node assay (LLNA) is currently recognized as a stand-alone test method for determining the skin sensitizing potential of chemicals. It has been incorporated into the official test guidelines published by some authorities, including the OECD. To avoid the use of radioisotopes,
β¦ LIBER β¦
Vehicle effects of DMSO in two strains of CBA mice in murine local lymph node assay
β Scribed by W. Wang-Fan; L.G. Ullmann; E. Deparade; J. Rapaport
- Book ID
- 119378651
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 66 KB
- Volume
- 164
- Category
- Article
- ISSN
- 0378-4274
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## Abstract Oronasal administration of MSVβH produced pathological changes in the lungs, mediastinum, gastric mucosa, spleen and brain. The early pulmonary changes showed intraβalveolar haemorrhage, then organization forming a βgranulomaβ and finally a circumscribed lesion containing predominantly