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Vectorised transport of drugs: Synthesis of a new glycosyl derivative of β-cyclodextrin.

✍ Scribed by Hélène Parrot-Lopez; Hervé Galons; Anthony W. Coleman; Jacqueline Mahuteau; Marcel Miocque

Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
229 KB
Volume
33
Category
Article
ISSN
0040-4039

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A selective, versatile, robust methodology for bifunctionalization of b-cyclodextrin is achieved allowing the attachment of peptides in varying C-and/or N-terminal combinations on resin using Fmoc SPPS. Two linkers are attached to cyclodextrin enabling selective binding to the resin (or a peptide at