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Vascular Smooth Muscle Cell Proliferation and Regrowth after Mechanical Injury in Vitro Are. Egr-1/NGFI-A-Dependent

✍ Scribed by Fernando S. Santiago; David G. Atkins; Levon M. Khachigian


Book ID
117022581
Publisher
American Society for Investigative Pathology
Year
1999
Tongue
English
Weight
569 KB
Volume
155
Category
Article
ISSN
0002-9440

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## Abstract Smooth muscle cell (SMC) migration and proliferation are key events in the pathogenesis of atherosclerotic and post‐angioplasty restenotic lesions. Mechanical injury to the artery wall induces the SMC expression of the zinc finger transcription factor, early growth response factor‐1 (Eg