Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity
โ Scribed by Chen, Lu; Hamrah, Pedram; Cursiefen, Claus; Zhang, Qiang; Pytowski, Bronislaw; Streilein, J Wayne; Dana, M Reza
- Book ID
- 109931593
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 739 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1078-8956
- DOI
- 10.1038/nm1078
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๐ SIMILAR VOLUMES
The opinions and assertions contained herein are the expressed views of the authors and are not to be construed as official or reflecting the views of the Departments of the Army or Defense.
## Abstract ## BACKGROUND Vascular endothelial growth factor C (VEGFโC) plays an important role in lymphangiogenesis and activates VEGF receptor 3 (VEGFRโ3). By contrast, lymphatic spread is an important prognostic factor in patients with nonsmall cell lung carcinoma (NSCLC). The objective of the
## Abstract ## Background and Methods. VEGF proteins and their receptors are involved in tumor vessel neoformation. The third VEGF receptor, VEGFR3 (fltโ4) is important during both blood vessel development and lymphatic vessel formation. Because HNSCC preferentially metastasizes to regional lymph