Vascular disrupting agents
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M.J. Pilat; P.M. LoRusso
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Article
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2006
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John Wiley and Sons
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English
โ 175 KB
It has been well established that a functioning vascular supply is essential for solid tumor growth and metastases. In the absence of a viable vascular network, tumors are unable to grow beyond a few millimeters and therefore remain dormant. Initiation of angiogenesis allows for continued tumor grow