The use of [11C]diazomethane for labelli
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C. Crouzel; A. Syrota
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Article
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1990
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Elsevier Science
β 172 KB
PN 200-l 10 (Isrodipine). a calcium channel antagonist, was labelled with "C (I, 2 20.4 min) by a reaction between [" Cldiazomethane and the carboxyt precursor. The ["C]CH2Nz is prepared in two stages from ["CICH,: ["C]CH,~["C]CHCI,~["C]CHZN,. When a mixture of nitrogen (95%) and hydrogen (5%) is i