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Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia

✍ Scribed by Anand P. Chokkalingam, Catherine Metayer, Ghislaine A. Scelo, Jeffrey S. Chang, Kevin Y. Urayama, Melinda C. Aldrich, Neela Guha, Helen M. Hansen, Gary V. Dahl, Lisa F. Barcellos, John K. Wiencke, Joseph L. Wiemels, Patricia A. Buffler

Book ID
113062734
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
218 KB
Volume
23
Category
Article
ISSN
0957-5243

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## Abstract Xenobiotic and folate metabolic pathways are important for the maintenance of genetic stability and may influence susceptibility to the development of childhood acute lymphoblastic leukaemia (ALL). In this study, we investigated 10 polymorphisms in 6 genes (__GSTM1__‐present/null, __GST