Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia
β Scribed by Nousome, Darryl; Lupo, Philip J.; Okcu, M. Fatih; Scheurer, Michael E.
- Book ID
- 120937841
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 201 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0145-2126
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π SIMILAR VOLUMES
The interindividual variation in the activity of xenobiotic metabolizing enzymes and DNA repair genes could modify an individual's risk of recurrent malignancy and response to therapy. We investigated whether ALL outcome was related to polymorphisms in genes CYP2D6, MPO, EPHX1, NQO1, TS, XPD and XRC
## Abstract The Australian Study of Causes of Acute Lymphoblastic Leukemia in Children (AusβALL) was designed to test the hypothesis, raised by a previous Western Australian study, that maternal folic acid supplementation during pregnancy might reduce the risk of childhood acute lymphoblastic leuke
## Abstract ## BACKGROUND Few studies have examined the risk of childhood acute lymphoblastic leukemia (ALL) associated with parental medication use. As part of a large caseβcontrol study conducted by the Children's Cancer Group, we evaluated the association between maternal and paternal medicatio