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Variation in plasma levels of insulin-like growth factor-I (IGF-I) in lingcod: relationships among season, size, and gonadal steroids

✍ Scribed by Anne H. Beaudreau; Kelly S. Andrews; Donald A. Larsen; Graham Young; Brian R. Beckman


Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
555 KB
Volume
158
Category
Article
ISSN
0025-3162

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## Abstract Epidemiological observations suggest that insulin‐like growth factor‐I (IGF‐I), a potent mitogenic and anti‐apoptotic peptide, plays a role in the etiology of breast cancer. Estrogen, which is crucial in breast carcinogenesis, both regulates and is influenced by IGF‐I family. A case‐con