Insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) play an important role in cell growth and differentiation. Clinical and epidemiological studies have indicated that measuring IGFs and IGFBPs in blood has potential implications in assessing growth-related abnormalities and risks o
β¦ LIBER β¦
Serum levels of insulin-like growth factors (IGF-I and IGF-II) and their binding protein (IGFBP-3) are not elevated in pancreatic cancer
β Scribed by James D. Evans; Margaret C. Eggo; Ian A. Donovan; Simon R. Bramhall; John P. Neoptolemos
- Publisher
- Springer US
- Year
- 1997
- Tongue
- English
- Weight
- 515 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1941-6628
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Insulin-like growth factor binding protein (IGFBP)-3 effects proliferation and differentiation of numerous cell types by binding to insulin-like growth factors (IGF) and attenuating their activity or by directly affecting cells in an IGFindependent manner. Consequently, IGFBPs produced by specific c