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Variable effect of ursodeoxycholic acid on cyclosporin absorption after orthotopic liver transplantation

โœ Scribed by Mohammed N. Al-Quaiz; John G. O'Grady; J. Michael Tredger; Roger Williams


Publisher
Springer
Year
1994
Tongue
English
Weight
508 KB
Volume
7
Category
Article
ISSN
0934-0874

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Bile acid metabolism and biliary secretion were characterized in the b t 2 wk after orthotopic liver traasplantation in 16 patients receiving cyclosporine and in five patients receiving FK 606. Analyses were performed on hepatic bile obtained by T-tube d r a values obtained were compared with litera

Effect of pretransplantation ursodeoxych
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As ursodeoxycholic acid (UDCA) delays the need for transplantation, this could result in patients with more comorbid disease, therefore more likely to have a worse outcome posttransplantation. The aim of this study is to compare posttransplantation outcome in patients who received UDCA versus placeb