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Variable effect of streptozotocin-diabetes on the growth of hamster pancreatic cancer (H2T) in the Syrian hamster and nude mouse

✍ Scribed by William E. Fisher; Peter Muscarella; Laszlo G. Boros; William J. Schirmer


Book ID
117221104
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
42 KB
Volume
123
Category
Article
ISSN
0039-6060

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Administration o f the nitrosamine carcinogen N-nitroso-bis (2-oxopropy 1) amine (BOP) by subcutaneous injection (5 mg/kg/week) led to the development of invasive pancreatic ductular adenocarcinoma in 100% of normal Syrian hamsters by 24 weeks. Pretreatment of a second group of hamsters with the bet