## Abstract The hepatotoxic and lipid peroxidative potentials of __t__โbutyl hydroperoxide (__t__โBuOOH) towards isolated perfused rat livers were investigated at doses of 1 and 3 mmol I^โ1^. __t__โBuOOH led to a concentrationโdependent release of cytosolic (glutamateโpyruvate transaminase and lact
Vanadate-induced toxicity towards isolated perfused rat livers: the role of lipid peroxidation
โ Scribed by M. Younes; O. Strubelt
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 629 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0300-483X
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The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in
## Abstract The effect and possible mechanism of action of vanadate on the isolated pulmonary arterial rings of normal rats were studied. Pulmonary arterial rings contracted in response to vanadate (0.1โ1 mM) in a concentrationโdependent manner. Preincubation of the pulmonary arterial rings with 1