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Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: A review

✍ Scribed by M. F. B. Silva; C. C. P. Aires; P. B. M. Luis; J. P. N. Ruiter; L. IJlst; M. Duran; R. J. A. Wanders; I. Tavares de Almeida

Publisher
Springer
Year
2008
Tongue
English
Weight
378 KB
Volume
31
Category
Article
ISSN
0141-8955

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Amniocytes isolated from two pregnancies at risk for fatty acid oxidation defects were incubated with stable isotopically labelled palmitate, in the presence of L-carnitine, to probe that pathway. The labelled acylcarnitines were then quantitated using tandem mass spectrometry. Amniocytes from a pre