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Validity of (−)-[3H]-CGP 12177A as a radioligand for the ‘putative β4-adrenoceptor’ in rat atrium

✍ Scribed by Doreen Sarsero; Peter Molenaar; Alberto J. Kaumann


Book ID
110003386
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
515 KB
Volume
123
Category
Article
ISSN
0007-1188

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S-[1-(2,3-Diaminophenoxy)]-3'-(N-t-butylamino)propan-2'-ol has been synthesized in three steps from 2,3-dinitro-phenol and the chiral auxiliary, S-glycidyl-3-nitrobenzenesulphonate, to provide a precursor for labelling S-(3'-t-butylamino-2'-hydroxypropoxy)-benzimidazol-2-one (S-CGP 12177) with the s