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Characterization of [3H]CP-96,501 as a Selective Radioligand for the Serotonin 5-HT1B Receptor: Binding Studies in Rat Brain Membranes

✍ Scribed by B. Kenneth Koe; Lorraine A. Lebel; Carol B. Fox; John E. Macor


Book ID
111177658
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
811 KB
Volume
58
Category
Article
ISSN
0022-3042

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✍ John E. Macor; Carol A. Burkhart; Lorraine A. Lebel; B. Kenneth Koe; Phillip M. 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 431 KB

## Abstract The synthesis of [^3^H]CP‐96,501 [5‐(2,3‐ditritiopropoxy)‐3‐(1,2,5,6‐tetrahydropyrid‐4‐yl)indole], a selective radioligand for the serotonin (5‐HT~1B~) receptor and analog of RU‐24,969, is described. 5‐Hydroxyindole is converted in two steps to 5‐(2‐propenyloxy)‐3‐(N‐__t__‐butoxycarbony