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Binding studies with the 5-HT1B receptor agonist [3H]CP-96,501 in brain tissues

✍ Scribed by Lorraine A. Lebel; Dr. B. Kenneth Koe


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
737 KB
Volume
27
Category
Article
ISSN
0272-4391

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## Abstract The synthesis of [^3^H]CP‐96,501 [5‐(2,3‐ditritiopropoxy)‐3‐(1,2,5,6‐tetrahydropyrid‐4‐yl)indole], a selective radioligand for the serotonin (5‐HT~1B~) receptor and analog of RU‐24,969, is described. 5‐Hydroxyindole is converted in two steps to 5‐(2‐propenyloxy)‐3‐(N‐__t__‐butoxycarbony