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Binding and uptake studies with [3H]CP-93, 129, a radiolabeled selective 5-HT1B receptor ligand

✍ Scribed by Dr. B. Kenneth Koe; Lorraine A. Lebel; Carol B. Fox; John E. Macor


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
496 KB
Volume
25
Category
Article
ISSN
0272-4391

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Synthesis of [3H]CP-93,129: A selective
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## Abstract The synthesis of [^3^H]‐CP‐93,129, a potent radioligand for the serotonin 5‐HT~1B~ receptor, is described. 5‐Butoxypyrrolo[3,2‐b]pyridine (2) is converted in 3 steps to 5‐butoxy‐1‐phenylsulfonyl‐2‐tritiopyrrolo[3,2‐b]pyridine (3c) via lithiation of C2, iodination of that anion, and trit

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