๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

โœ Scribed by Smith, Catherine C.; Wang, Qi; Chin, Chen-Shan; Salerno, Sara; Damon, Lauren E.; Levis, Mark J.; Perl, Alexander E.; Travers, Kevin J.; Wang, Susana; Hunt, Jeremy P.

Book ID
111928178
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
517 KB
Volume
485
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Comorbidities and FLT3-ITD abnormalities
Comorbidities and FLT3-ITD abnormalities as independent prognostic indicators of survival in Elderly acute myeloid leukaemia patients
โœ Massimo Breccia; Anna Maria Frustaci; Laura Cannella; Caterina Stefanizzi; Rober ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 126 KB

## Abstract Elderly acute myeloid leukaemia (AML) patients have a dismal prognosis due to biological features of disease in itself and to presence of comorbidities. Aim of this study was to evaluate the prognostic impact of comorbidity prognostic score systems applied in our population of patients.

P080 Incidence of FLT-3 mutations in Ira
P080 Incidence of FLT-3 mutations in Iranian patients with acute myeloid leukaemia
โœ F. Zaker; M. Mohammadi; A. Kazemi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 58 KB

Mutations affecting NPM, FLT3 ITD and TKD were present in 25% (30/120), 22% (26/120) and 8/120 (7%), respectively. NPM mutations were most prevalent in patients with normal karyotype (24/52; 46%) and were associated with FLT3-ITD mutations (16/26; 62%). Regarding the prognostic significance of NPM a