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Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

✍ Scribed by Kehoe, Kaat; Verkerk, Robert; Sim, Yani; Waumans, Yannick; Van der Veken, Pieter; Lambeir, Anne-Marie; De Meester, Ingrid

Book ID
121236577
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
730 KB
Volume
443
Category
Article
ISSN
0003-2697

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Validation of a simple HPLC method for a
Validation of a simple HPLC method for assay of haplamine and its metabolites in plasma suitable for pharmacokinetic application in rats
✍ Sompheary Ea; Claude Aubert; Sarah Giacometti; Joseph Ciccolini; Chhan Siv; Hot πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 331 KB πŸ‘ 2 views

## Abstract A simple HPLC method with ultraviolet detection has been developed and validated for the simultaneous determination of haplamine and its metabolites (__trans__/__cis__‐3,4‐dihydroxyhaplamine) in rat. A liquid–liquid extraction was used to extract the compounds from rat plasma. The analy