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The detection of anti-erythropoietin antibodies in human serum and plasma: Part I. Validation of the protocol for a radioimmunoprecipitation assay

โœ Scribed by Richard Tacey; Anthony Greway; Janice Smiell; David Power; Arno Kromminga; Mohamed Daha; Nicole Casadevall; Marian Kelley


Book ID
113716674
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
284 KB
Volume
283
Category
Article
ISSN
0022-1759

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## Abstract Measuring low amounts of antiโ€erythropoietin antibodies (antiโ€EPO Abs) is important to evaluate the therapeutic safety of recombinant human erythropoietin (rhEPO). In this work, a simple, sensitive and highโ€throughput chemiluminescent (CL) imaging assay was developed for the detection o