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Validated RP-HPLC/UV method for the quantitation of abiraterone in rat plasma and its application to a pharmacokinetic study in rats

✍ Scribed by S. Vijay Kumar; G. Rudresha; Sandip Gurav; Mohd Zainuddin; Purushottam Dewang; Raghava Reddy Kethiri; Sriram Rajagopal; Ramesh Mullangi


Book ID
112013519
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
179 KB
Volume
27
Category
Article
ISSN
0269-3879

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## Abstract A specific, accurate, precise and reproducible high‐performance liquid chromatography (HPLC) method was developed for the estimation of ragaglitazar [(βˆ’) DRF 2725, NNC 61‐0029], a novel anti‐diabetic agent, in rat plasma. The assay procedure involved simple liquid/liquid extraction of r