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Development and Validation of an HPLC–UV Method for the Determination of Insulin in Rat Plasma: Application to Pharmacokinetic Study

✍ Scribed by Sheshala Ravi; Kok Khiang Peh; Yusrida Darwis; Bhavanasi Krishna Murthy; Thakur Raghu Raj Singh


Book ID
111790913
Publisher
Springer
Year
2007
Tongue
English
Weight
324 KB
Volume
66
Category
Article
ISSN
0009-5893

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## Abstract A specific, accurate, precise and reproducible high‐performance liquid chromatography (HPLC) method was developed for the estimation of ragaglitazar [(−) DRF 2725, NNC 61‐0029], a novel anti‐diabetic agent, in rat plasma. The assay procedure involved simple liquid/liquid extraction of r