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Validated LC-ESI-MS/MS Method for the Quantitation of Neopanaxadiol: a Novel Neuroprotective Agent fromPanax ginsengand Its Application to a Pharmacokinetic Study in Rat Plasma

✍ Scribed by Geng, Cong; Liu, Jihua; Guan, Qingxiang; Zhang, Ying; Meng, Qin; Sun, Deya; Sun, Yuequan; Wang, Jianwei; Zhou, Yihan; Yin, Jianyuan

Book ID
120355124
Publisher
Springer
Year
2013
Tongue
English
Weight
291 KB
Volume
76
Category
Article
ISSN
0009-5893

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Highly sensitive LC-MS/MS-ESI method for
Highly sensitive LC-MS/MS-ESI method for simultaneous quantitation of albendazole and ricobendazole in rat plasma and its application to a rat pharmacokinetic study
✍ Kuldeep Sharma; Murugesh Kandaswamy; Chandan Mithra; Ashok Kumar Meena; Sanjeev πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 628 KB

## ABSTRACT A highly sensitive and specific LC‐MS/MS‐ESI method was developed for simultaneous quantification of albenadazole (ABZ) and ricobendazole (RBZ) in rat plasma (50 μL) using phenacetin as an internal standard (IS). Simple protein precipitation was used to extract ABZ and RBZ from rat plas