Validated HPLC–MS–MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma—pharmacokinetic study
✍ Scribed by V. Bořek-Dohalský; J. Huclová; B. Barrett; B. Němec; I. Ulč; I. Jelínek
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 181 KB
- Volume
- 386
- Category
- Article
- ISSN
- 1618-2650
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A rapid, simple, sensitive and specific LC‐MS/MS method has been developed and validated for the simultaneous estimation of atorvastatin (ATO), amlodipine (AML), ramipril (RAM) and benazepril (BEN) using nevirapine as an internal standard (IS). The API‐4000 LC‐MS/MS was operated under t
An analytical method based on liquid–liquid extraction has been developed and validated for analysis of agomelatine in human plasma. Fluoxetine was used as an internal standard for agomelatine. A Betasil C18 (4.0 × 100 mm, 5 µm) column provided chromatographic separation of analytes followed by dete