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Vaginal absorption of hexachlorophene in the rat

✍ Scribed by C.P Chow; H.S Buttar; R.H Downie


Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
380 KB
Volume
10
Category
Article
ISSN
0300-483X

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Brain succinate dehydrogenase (SDH) activity was inhibited by in vitro hexachlorophene (HCP) with a half inhibitory concentration (IC 50 ) of 0.65 ‫‬ 10 ‫3‬ M. The HCP exerted noncompetitive inhibition at 0.5 mM (Ο½IC 50 ), uncompetitive inhibition at 0.65 mM (IC 50 ), and mixed-type inhibition at 0.