Transaminase inhibitors block glycolysis
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John Groelke; Harold Amos
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Article
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1984
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John Wiley and Sons
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English
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Two transaminase inhibitors, aminooxyacetate and cycloserine, inhibited the initiation of insulin-stimulated DNA synthesis in chick embryo fibroblasts. This inhibition was overcome when pyruvate (4 mM), oxaloacetate (4 mM), or alpha-ketobutyrate (10 mM) was included in the culture medium with hormon