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Uvm mutants of Escherichia coli K 12 deficient in UV mutagenesis

✍ Scribed by Steinborn, Gerhard

Publisher
Springer
Year
1978
Tongue
English
Weight
714 KB
Volume
165
Category
Article
ISSN
0026-8925

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✦ Synopsis

Selection for defective reversion induction, after UV treatment of E. coli K 12, yielded uvm mutants. These mutants exhibited highly reduced or no UV mutability for all loci tested although they were moderately and normally mutable by X-rays and EMS, respectively. Uvm mutations confer only a slight sensitivity to killing by UV and X-rays and no clear sensitivity to the lethal effect of HN2, EMS or MMS. Growth and viability of untreated uvm cells were normal. The properties of uvm mutants are discussed in relation to those of other relevant mutant types and to some actual problems of induced mutagenesis.

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Uvm mutants of Escherichia coli K12 defi
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