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UVB-specific regulation of gene expression in human melanocytic cells: cell cycle effects and implication in the generation of melanoma

✍ Scribed by E Ablett; J Pedley; P.A Dannoy; R.A Sturm; P.G Parsons

Book ID
114072393
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
618 KB
Volume
422
Category
Article
ISSN
0027-5107

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## Abstract The purpose of our study was to analyze the p53‐mediated response of human melanocytes and human melanoma cells to UVB (natural environmental carcinogen) or UVC irradiation (experimental carcinogen). A semi‐quantitative RT‐PCR method was developed to allow the analysis of the expression