Modulation of ICAM-1 expression by Ξ±-MSH
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R. Morandini; J. M. Boeynaems; S. J. Hedley; S. MacNeil; G. Ghanem
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Article
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1998
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John Wiley and Sons
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English
β 208 KB
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a-MSH, a proopiomelanocortin (POMC)-derived peptide, is known to be produced in the pituitary, the skin, and melanoma tumors and to possess many biological effects, mainly on melanocyte pigmentation and growth. Moreover, the melanocyte expresses adhesion molecules, including ICAM-1. The latter has b